What to know about Lilly's Portfolio of Non-Branded Insulins

Insulin Lispro Injection U-100

: Because it’s the same molecule as Humalog^® (insulin lispro injection), Lilly’s Insulin Lispro Injection U-100 helps control the blood sugar spikes that happen naturally when you eat. Lilly’s Insulin Lispro Injection U-100 (a fast-acting insulin) works to manage those blood sugar spikes and may help keep your sugar levels in balance. Lilly’s Insulin Lispro Injection U-100 is taken within 15 minutes before eating or right after eating a meal.

Insulin Lispro Injection is different than your long-acting insulin. Long-acting insulin helps control your blood sugar throughout the whole day. It's important to talk to your doctor about when and how often you should check your blood sugar levels.

Select Safety Information

Do not take Humalog or Insulin Lispro Injection if you have symptoms of low blood sugar (hypoglycemia) or an allergy to insulin lispro products or any of their ingredients.

: The Insulin Lispro Injection U-100 KwikPen is a small, lightweight pen that's prefilled with mealtime insulin. Since it shouldn't be refrigerated after the first use*, you can take it just about anywhere. You can carry it in a purse or slip it into a jacket or coat pocket. It's a good idea to always carry an extra pen.

For complete Instructions for Use of the Insulin Lispro Injection U-100 KwikPen, click here .

^*Once you start using Insulin Lispro Injection U-100 KwikPen, it should be stored at room temperature, below 86^˚F (30^˚C), and must be used within 28 days or be discarded, even if it still contains Insulin Lispro Injection U-100.

Select Safety Information

Do not reuse needles or share your insulin injection supplies with other people. This includes your prefilled pen for use by a single patient, cartridges, reusable pen that works with Lilly 3mL cartridges, needles, and syringes. You or the other person can get a serious infection. This can happen even if you change the needle.

: Lilly’s Insulin Lispro Injection U-100 may be injected under your skin in the stomach area, the back of your upper arms, upper legs, or buttocks (see diagram). Never inject Lilly’s Insulin Lispro Injection U-100 into a muscle or vein. Ask your doctor for help determining the most appropriate injection sites for you.

Be sure to use a different injection site each time and do not overuse any site.

Select Safety Information

Do not change the type of insulin you take or your dose, unless your doctor tells you to. This could cause low or high blood sugar, which could be serious. Do not inject your insulin into the exact same spot or where the skin has pit or lumps. Avoid injecting into thickened, tender, bruised, scaly, hard, scarred, or damaged skin.

: Everyone’s experience with mealtime insulin is different, but there are some things you can look out for.

Dose changes
Your Insulin Lispro Injection U-100 dose will probably change over time. Your doctor gave you a starting dose, but most people need to increase their dose over time.

Blood sugar variations
When you track your blood sugar every day, you will probably see different numbers all the time. These variations in your blood sugar from day to day are normal.

Changes are normal
Your blood sugar varies based on stress, what you eat, other medications, exercise, and other factors. Don’t be discouraged by changes in your blood sugar. With your doctor’s input, these variations may provide learning opportunities.

Select Safety Information

Humalog and Insulin Lispro Injection may cause serious side effects that can lead to death, such as low blood sugar. Low blood sugar can cause dizziness or light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, mood change, and hunger. If you are at risk of having severely low blood sugar, your doctor may prescribe a glucagon emergency kit. These are used when your blood sugar becomes too low and you are unable to take sugar by mouth. Glucagon helps your body release sugar into your bloodstream.

Insulin Lispro Protamine and Insuline Lispro Injectable Suspension Mix75/25 KwikPen (100 units/mL)

: Lilly’s Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 is a combination of fast- and longer-acting insulins that work together to help manage your blood sugar between meals and at night, as well as blood sugar spikes that can happen when you eat.

Note that Lilly’s Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 starts working faster than other insulins that contain regular human insulin.

It's important to take Lilly’s Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 within 15 minutes before eating a meal to help prevent low blood sugar.

Select Safety Information

Do not take Humalog, Insulin Lispro Injection, Humalog Mix50/50, Humalog Mix75/25, or Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 if you have symptoms of low blood sugar (hypoglycemia), or an allergy to insulin lispro products or any of their ingredients.

: Insulin mixes—such as Lilly’s Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPen—combine fast-acting and longer-acting insulins to give you the benefit of both insulins. Mixes help manage your blood sugar between meals and at night, as well as blood sugar spikes that can happen when you eat.

: Lilly’s Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPen is a small, lightweight pen that’s prefilled with combinations of fast- and longer-acting insulin. Plus, since it shouldn't be refrigerated after the first use^*, you can take it just about anywhere. You can carry it in your purse, backpack, or pocket because it’s the size of a marker. It’s a good idea to always carry an extra pen. Unused pens stored at room temperature, below 86°F (30°C), should be thrown away after 10 days.

For complete Instructions for Use of the Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPen, click here.

^*Once you start using Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPen, it should be stored at room temperature, below 86˚F (30˚C), and must be used within 10 days or be discarded, even if it still contains Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25.

Select Safety Information

Do not reuse needles or share your insulin injection supplies with other people. This includes your prefilled pen for use by a single patient, cartridges, reusable pen that works with Lilly 3mL cartridges, needles, and syringes. You or the other person can get a serious infection. This can happen even if you change the needle.

: Lilly’s Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 may be injected under your skin in the stomach area, the back of your upper arms, upper legs, or buttocks (see diagram). Never inject Lilly’s Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 into a muscle or vein. Ask your doctor for help determining the most appropriate injection sites for you.

Be sure to use a different injection site each time and do not overuse any site.

Select Safety Information

Do not change the type of insulin you take or your dose, unless your doctor tells you to. This could cause low or high blood sugar, which could be serious. Do not inject your insulin into the exact same spot or where the skin has pit or lumps. Avoid injecting into thickened, tender, bruised, scaly, hard, scarred, or damaged skin.

: Everyone’s experience with combinations of fast- and longer-acting insulin is different, but there are some things you can look out for.

Dose changes
Your dose will probably change over time. Your doctor gave you a starting dose, but most people need to increase their dose over time.

Blood sugar variations
When you track your blood sugar every day, you will probably see different numbers all the time. These variations in your blood sugar from day to day are normal.

Changes are normal
Your blood sugar varies based on stress, what you eat, other medications, exercise, and other factors. Don’t be discouraged by changes in your blood sugar. With your doctor’s input, these variations may provide learning opportunities.

Select Safety Information

Humalog, Insulin Lispro Injection, Humalog Mix50/50, Humalog Mix75/25, and Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 may cause serious side effects that can lead to death such as low blood sugar. Low blood sugar can cause dizziness or light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, mood change, and hunger.

If you are at risk of having severely low blood sugar, your doctor may prescribe a glucagon emergency kit. These are used when your blood sugar becomes too low and you are unable to take sugar by mouth. Glucagon helps your body release sugar into your bloodstream.

Insulin Lispro Injection Junior KwikPen^®

: Lilly’s Insulin Lispro Injection Junior KwikPen is an insulin pen that offers the combined benefits of a prefilled disposable pen with rapid-acting insulin and half-unit dosing. Insulin Lispro Injection Junior KwikPen is different from Insulin Lispro Injection KwikPen because it can dose in half-unit increments. Plus, because it's a KwikPen, it shouldn’t be refrigerated after the first use^*, and you can take it just about anywhere. You can carry it in your purse, your child’s backpack, or a pocket because it’s the size of a marker. Remember to always carry an extra pen.

Lilly’s Insulin Lispro Injection Junior KwikPen offers fast-acting insulin, right when you need it, to help control your child’s diabetes.

After your child uses Lilly’s Insulin Lispro Injection Junior KwikPen for the first time, do not put it back in the refrigerator. Lilly’s Insulin Lispro Injection Junior KwikPen is good for 28 days after the first use. After that, it should be discarded, even if insulin remains^*. Always call to make sure your pharmacy has Lilly’s Insulin Lispro Injection Junior KwikPen (in the quantity you need) in stock. If not, they can order them for you.

^*Once you start using Insulin Lispro Injection Junior KwikPen, it should be stored at room temperature, below 86˚F (30˚C), and must be used within 28 days or be discarded, even if it still contains Insulin Lispro Injection U-100.

Select Safety Information

Do not take Humalog or Insulin Lispro Injection if you have symptoms of low blood sugar (hypoglycemia) or an allergy to insulin lispro products or any of their ingredients.

: Lilly's Insulin Lispro Injection Junior KwikPen is a small, lightweight pen that’s prefilled with mealtime insulin. After the first use^*, the pen shouldn’t be refrigerated, which makes it simple to bring it along anywhere you and your child may go. You can carry it in your purse, your child’s backpack, or slip it into a jacket or coat pocket. It’s a good idea to always carry an extra pen.

For complete Instructions for Use of the Insulin Lispro Junior KwikPen, click here.

^*Once you start using Insulin Lispro Junior KwikPen, it should be stored at room temperature, below 86˚F (30˚C), and must be used within 28 days or be discarded, even if it still contains Insulin Lispro Injection U-100.

Select Safety Information

Do not reuse needles or share your insulin injection supplies with other people. This includes your prefilled pen for use by a single patient, cartridges, reusable pen that works with Lilly 3mL cartridges, needles, and syringes. You or the other person can get a serious infection. This can happen even if you change the needle.

: Lilly’s Insulin Lispro Injection may be injected under your child’s skin in the stomach area, the back of their upper arms, upper legs, or buttocks (see diagram). Never inject Lilly’s Insulin Lispro Injection into your child’s muscle or vein. Ask your doctor for help in determining the most appropriate injection sites for your child.

Be sure to use a different injection site each time and do not overuse any site.

Select Safety Information

Do not change the type of insulin you take or your dose, unless your doctor tells you to. This could cause low or high blood sugar, which could be serious. Do not inject your insulin into the exact same spot or where the skin has pit or lumps. Avoid injecting into thickened, tender, bruised, scaly, hard, scarred, or damaged skin.

: Everyone’s experience with mealtime insulin is different, but there are some things you can look out for.

Dose changes

Your child's Insulin Lispro Injection dose will probably change over time. Your doctor gave you a starting dose, but most people need to increase their dose over time.

Blood sugar variations
When you track your blood sugar every day, you will probably see different numbers all the time. These variations in your blood sugar from day to day are normal.

Changes are normal
Your blood sugar varies based on stress, what you eat, other medications, exercise, and other factors. Don’t be discouraged by changes in your blood sugar. With your doctor’s input, these variations may provide learning opportunities.

Select Safety Information

Humalog and Insulin Lispro Injection may cause serious side effects that can lead to death, such as low blood sugar. Low blood sugar can cause dizziness or light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, mood change, and hunger. If you are at risk of having severely low blood sugar, your doctor may prescribe a glucagon emergency kit. These are used when your blood sugar becomes too low and you are unable to take sugar by mouth. Glucagon helps your body release sugar into your bloodstream.